High Magnetic Field Lab, CAS
P.O. Box 1110, 350 Shushanhu Road, Hefei, 230031

Tel: 0551-65591485 +86 -158 3886 0677 (Mobile)
Email: lianghm@hfcas.ac.cn, huamin.liang@outlook.com

EDUCATION BACKGROUND

Oct. 2013 ,Ph.D. in Biopharmaceutics, Faculty of Pharmacy, University of Helsinki, Finland

Thesis: Non-labeled surface sensitive techniques as platforms for pharmaceutical nanotechnology research (nanoparticle drug delivery systems and nanoscale films)

Supervisors：Prof. Marjo Yliperttula & Dr. Tapani Viitala

Dec. 2010, Doctor in Biomedical Engineering, College of Bioengineering, Chongqing University, P.R. China

Thesis：SPR and QCM biosensing techniques for studying surface binding behavior of targeted liposome

Supervisor: Prof. Bochu Wang

Jun. 2004, Master in Food Science and Technology, Henan University of Technology, P.R. China

Supervisor: Prof. Shaojun Tian

Jun. 2000, Bachelor in Chemistry and Engineering of Edible Oil, Henan University of Technology, P.R. China

 

Professional Experiences/Previous Employments

2015.12-present, Associate Professor, Hefei Institutes of Physical Science, Chinese Academy of Sciences (CAS), Hefei, Anhui, P.R. China

• Research interest: nanoparticle drug delivery for kinase inhibitor anticancer drugs

2013.11-2014.12, Postdoctoral Research Fellow , Department of Chemistry & Bioengineering, Tampere University of Technology, Finland

• Biomimetic Membranes as Cell Culture Platforms for Regenerative Medicine and Research on Exocytosis and Endocytosis of Microvesicles (MVs).

• Mechanisms of nanoparticle gene delivery: characterization of nanoparticles and their transport mechanisms.

• Liposomes with gold nanoparticles for time and location controlled drug release.

2009.10-2013.10, Researcher/Ph.D. student, Division of Biopharmaceutics & Pharmacokinetics, Faculty of Pharmacy, University of Helsinki, Finland

• Molecularly Controlled Planar Cell Surface Models: Platform for Targeted Drug and Gene Delivery and Release Optimization.

• Printable Pharmaceuticals for Drug Delivery.

2007.10-2009.09, Visiting Researcher/Ph.D. student , Division of Biopharmaceutics & Pharmacokinetics, Faculty of Pharmacy, University of Helsinki, Finland

• Optimization and applicability of the Surface Plasmon Resonance (SPR) and Quartz Crystal Microbalance (QCM) methodologies for nanotechnology research.

2005.09-2007.09, Ph.D. student , College of Bioengineering, Chongqing University, China

• Biological antifouling paint with controlled release for the coating of ship surface

2004.05-2005.08, Researcher, Center of Research and Development, Baixiang Food Group Ltd., Zhengzhou, China

• Development of new instant noodle product and improvement of manufacturing process

 

PUBLICATIONS

1. Anni E. Sorkio*, Elina P. Vuorimaa-Laukkanen, Hanna M. Hakola, Huamin Liang, Tiina A. Ujula, Juan José Valle-Delgado, Monika Österberg, Marjo L. Yliperttula, Heli Skottman, Biomimetic Collagen I and IV double layer Langmuir-Schaefer films as microenvironment for human pluripotent stem cell derived retinal pigment epithelial cells, Biomaterials 2015, 51: 257-269.
2. Tatu Lajunen*, Lauri Viitala, Leena-Stiina Kontturi, Timo Laaksonen, Huamin Liang, Elina Vuorimaa-Laukkanen, Tapani Viitala, Xavier Le Guével, Marjo Yliperttulaa, Light induced cytosolic drug delivery from liposomes with gold nanoparticles, Journal of Controlled Release 2015, 203: 85-98.
3. Peng Liu, Tapani Viitala, Alma Kartal-Hodzic, Huamin Liang, Timo Laaksonen, Jouni Hirvonen, Leena Peltonen*, Interaction Studies Between Indomethacin Nanocrystals and PEO/PPO Copolymer Stabilizers, Pharmaceutical Research 2015, 32(2): 628-639.
4. Niko Granqvist#, Huamin Liang#, Terhi Laurila, Janusz Sadowski, Marjo Yliperttula, Tapani Viitala*, Characterizing Ultrathin and Thick Organic Layers by Surface Plasmon Resonance Three-Wavelength and Waveguide Mode Analysis, Langmuir 2013, 29(27): 8561-8571.
5. Huamin Liang*, Jussi-Pekka Tuppurainen, Julia Lehtinen, Tapani Viitala, Marjo Yliperttula, Non-labeled monitoring of targeted liposome interactions with a model receptor surface: Effect of flow rate and water content, European Journal of Pharmaceutical Sciences 2013, 50(3-4): 492-501.
6. Tapani Viitala, Huamin Liang, Mayur Gupta, Thomas Zwinger, Marjo Yliperttula, Alex Bunker*, Fluid dynamics modeling for synchronizing surface plasmon resonance and quartz crystal microbalance as tools for biomolecular and targeted drug delivery studies, Journal of Colloid and Interface Science 2012, 378(1): 251-259.
7. Julia Lehtinen*, Mari Raki, Kim A. Bergström, Päivi Uutela, Katariina Lehtinen, Annukka Hiltunen, Jere Pikkarainen, Huamin Liang, Sari Pitkänen, Ann-Marie Määttä, Raimo A. Ketola, Marjo Yliperttula, Thomas Wirth, Arto Urtti, Pre-Targeting and Direct Immunotargeting of Liposomal Drug Carriers to Ovarian Carcinoma, Plos One 2012, 7(7): e41410.
8. Tapani Viitala*, Niko Granqvist, Huamin Liang, Marjo Yliperttula,, Real-time label-free monitoring of drug- or nanoparticle-cell interactions, CRS Newsletter 2012, 29 (6): 14-16.
9. Huamin Liang, Heini Miranto, Niko Granqvist, Janusz W. Sadowskic, Tapani Viitalab, Bochu Wang*, Marjo Yliperttula*, Surface plasmon resonance instrument as a refractometer for liquids and ultrathin films, Sensors and Actuators B: Chemical 2010, 149(1): 212-220.

Issued Patents

2. Bochu Wang, Huamin Liang, Fengwei Yuan, Chao Zheng et al. Bio-antifouling coating based on controlled and sustained release, CN101186767B. (in China, 2010)
3. Shuangkou Chen, Bochu Wang, Taigang Zhou, Yingzhu Feng and Huamin Liang. A new method of antifouling and anticorrosion based on biotechnology and electrochemistry, CN100551978C. (in China, 2010)

Conference

* PA=Presenting Author

1. L. Peltonen, P (PA). Liu, T. Viitala, A. Kartal-Hodzic, H. Liang, T. Laaksonen and J. Hirvonen. Surface plasmon resonance and contact angle measurements for drug-excipient interaction studies. The 10th Central European Symposium on Pharmaceutical Technology (CESPT 2014), September 18th-20th, 2014, Portoroz, Slovenia. Oral poster presentation.
2. Huamin Liang (PA), Tapani Viitala, Marjo Yliperttula. Label-free sensor techniques for specific interaction of targeted nanoparticle with model surface. 3rd International Conference on Bio-Sensing Technology, May 12-15, 2013, Sitges (near Barcelona), Spain. Poster presentation.
3. Annika Jokinen, Alma Kartal, Huamin Liang, Jouko Peltonen, Petri Ihalainen, Niko Granqvist and Tapani Viitala (PA). Methodology to study interaction of drug substances with paper coating chemicals – A perspective for printed pharmaceuticals. 24th Annual Symposium of the Finnish Society of Physical Pharmacy, Feb. 7 2013, Turku, Finland.  Poster presentation.
4. Huamin Liang (PA), Tapani Viitala, Jussi-Pekka Tuppurainen, Julia Lehtinen and Marjo Yliperttula. SPR & QCM biosensor for investigating the binding behaviors of targeted liposome to surface under shear flow. Farmasian Päivät (Pharmacy Day) 2012, Nov. 23-25, 2012, Helsinki. Poster presentation.
5. T. Viitala (PA), N. Granqvist, H. Liang, J. W. Sadowski,, I. M. Vikholm-Lundin,, K. Tappura,, W. M. Albers. Determination of thickness and optical constants of thin films by dual medium and multi-wavelength SPR spectroscopy, 16th Int. Conf. on Sold Films and Surfaces, July 2012
6. Huamin Liang (PA), Tapani Viitala, Jussi-Pekka Tuppurainen, Julia Lehtinen and Marjo Yliperttula. SPR & QCM biosensor for investigating the binding behaviors of targeted liposome to surface under shear flow. 17th IUPAB International Biophysics Congress, Oct. 30 – Nov. 3, 2011, Beijing, China. Poster presentation.

Grants/Rewards

•       Travel grant from FinPharma Doctoral Program-Pharmacy (FPDP-P) (2011.10)
•       Travel grant from FPDP-P (2013. 05)
•       Two-year grant from Chinese Scholarship Council (CSC) for supporting the study of doctoral student abroad (2007.09)
•       Research funding from Innovative research program of Chongqing University for Ph.D. student
•       Rewards for excellent student during my bachelor study for six times（1996.09-2000.06）