Binhua Li
High Magnetic Field Lab, CAS
350 Shushanhu Road, Hefei, 230031
Tel: 0551-65593617
Email: jintianjiuhao666@163.com
EDUCATION BACKGROUND
M.S. (2008-2011), Polymer Chemistry and Physics College of Chemistry & Chemical Engineering, Anhui University, China
B.S. (2003-2007), Chemistry College of Chemistry and Materials Science, Anhui Normal University, China
Occupation training (2013) Department of Chemistry, Vanderbilt University, USA
Joint training (2009-2011) Chemistry Shanghai Institute of Organic Chemistry, CAS, China
EXPERIENCE
Assistant Professor(2012.6-present) High Magnetic Field Laboratory, CAS, Anhui, China
Teacher (2007-2008) Fengshan Middle School, Xiaoxian, Anhui, China
PUBLICATIONS
- Binhua Li＃, Xiaomin Cheng, Chaozhong Li＊, Silver-Catalyzed Chlorination of Aromatic Compounds. Chin. J. Chem. 2011, 29: 2809—2812.
- Hong Wu＃, Wenchao Wang＃, Feiyang Liu＃, Ellen E. Weisberg＃, Bei Tian, Yongfei Chen, Binhua Li, Aoli Wang , Beilei Wang, Zheng Zhao, Douglas W. McMillin, Chen Hu, Hong Li, Jinhua Wang, Yanke Liang, Sara J. Buhrlage, Junting Liang, Jing Liu, Guang Yang, Jennifer R. Brown, Steven P. Treon, Constantine S. Mitsiades, James Griffin, Qingsong Liu＊, Nathanael S. Gray＊, Discovery of a Potent, Covalent BTK Inhibitor for B-Cell lymphoma. ACS Chem. Biol. 2014, 9: 1086-1091.
- Hong Wu＃, Chen Hu＃, Aoli Wang＃, Ellen L. Weisberg＃, Yongfei Chen＃, Cai-Hong Yun, Wenchao Wang, Yan Liu, Xiaochuan Liu, Bei Tian, Jinhua Wang, Zheng Zhao, Yanke Liang, Binhua Li, Li Wang, Beilei Wang, Cheng Chen, Sara J. Buhrlage, Ziping Qi, Fengming Zou, Atsushi Nonami, Yuyang Li, Stacey M. Fernandes, Sophia Adamia, Richard M. Stone, Ilene A. Galinsky, Xianhuo Wang, Guang Yang, James D. Griffin, Jennifer R. Brown, Michael J. Eck, Jing Liu＊, Nathanael S. Gray＊, Liu Qingsong＊. Discovery of a BTK/MNK Dual Inhibitor for Lymphoma and Leukemia. Leukemia 2016, 30(1): 173-181.
- Binhua Li＃, Aoli Wang＃, Juan Liu＃, Ziping Qi＃, Xiaochuan Liu＃, Kailin Yu＃, Hong Wu, Cheng Chen, Chen Hu, Wenchao Wang, Jiaxin Wu, Zhenquan Hu, Ling Ye, Fengming Zou, Feiyang Liu, Beilei Wang, Li Wang, Tao Ren, Shaojuan Zhang, Mingfeng Bai, Shanchun Zhang, Jing Liu＊, Qingsong Liu＊. Discovery of N-((1-(4-(3- (3-((6,7-dimethoxyquinolin-3-yl)oxy)phenyl)ureido)-2-(trifluoromethyl)phenyl)piperidin-4-yl)methyl)propionamide (CHMFL-KIT-8140) as a Highly Potent Type II Inhibitor Capable of Inhibiting the T670I "Gatekeeper" Mutant of cKIT Kinase. J. Med. Chem. 2016, (59)18: 8456-8472
- Feiyang Liu＃, Jinhua Wang＃, Xingxing Yang＃, Binhua Li＃, Hong Wu, Shuang Qi, Cheng Chen, Xiaochuan Liu, Kailin Yu, Wenchao Wang, Zheng Zhao, Aoli Wang, Yongfei Chen, Li Wang, Nathanael S. Gray, Jing Liu＊, Xin Zhang＊, Qingsong Liu＊ Discovery of a Highly Selective STK16 Kinase Inhibitor. ACS Chem. Biol. 2016, 11, 1537-1543.
PCT applications
- "A new type of FLT3 kinase inhibitors and its application", Liu, Qingsong; Liu Jing; Li Binhua; Wang Aoli; Wu Hong; Chen Cheng;Wang Wenchao; Hu Chen; Zhao Zheng; Yu Kailin;Wang Beilei; Wang Li. (2015) PCT/CN2015/090306
- "Triciribine and its metabolite is sensitive to FLT3-ITD dependent AML", Liu, Qingsong; Liu Jing;Wang Aoli; Wu Hong;Wang Wenchao; Chen Cheng;Hu Chen; Li Binhua; Ziping Qi; Yu Kailin;Wang Li. (2015) PCT/CN2015/092600
PCT applications
- 一类新型的FLT3激酶抑制剂及其用途
发明人：刘青松， 刘静， 李滨华, 王傲莉，吴宏，陈程，王文超，胡晨，赵铮，余凯琳，王蓓蕾，王黎 。专利受理号：2201510608850.4. - 曲西立滨（Triciribine）及相关代谢产物对FLT3突变的急性白血病的应用
发明人：刘青松， 刘静， 王傲莉， 吴宏， 王文超，陈程，胡晨，李滨华，齐紫平，余凯琳，王黎。专利受理号：2201510665488.4.