Rui jin

PostDoc

High Magnetic Field Lab, CAS
P.O. Box 1110, 350 Shushanhu Road, Hefei, 230031

Tel: 86-551-65595013
Email: Jinr@cmpt.ac.cn

EDUCATION BACKGROUND

2016/09-2020/01 Fudan Univerisity, School of Pharmacy, Ph.D.

2013/09-2016/07 Anhui Medical University, School of Basic Medicine. Master.

2009/09-2013/07 Wannan Medical College, Department of pharmacy, B.S.

 

RESEARCH EXPERIENCE

2020/09-now, Postdoctoral Associate, Innovative drug research center of Institute of health and medical technology.

PUBLICATIONS

  1. Rui Jin#, Liang Liu, Yun Xing, Tao Meng, Lanping Ma, Jinpeng Pei, Ying Cong, Xuesai Zhang, Zhiqiang Ren, Xin Wang, Jingkang Shen, Ker Yu*. DualMechanisms of Novel CD73-Targeted Antibody and Antibody–Drug Conjugate in Inhibiting Lung Tumor Growth and Promoting Antitumor Immune-Effector Function. Mol. Cancer Ther. 2020 Sep 17. doi: 10.1158/ 1535-7163.
  2. Xing Y, Ren ZQ, Rui Jin, Liu L, Pei JP, Yu K. Therapeutic efficacy and mechanism of CD73-TGFβ dual-blockade in a mouse model of triple-negative breast cancer. Acta. Pharmacol Sin. 2022. doi: 10.1038/s41401-021-00840-z.
  3. Mingcong Li, Rui Jin#, Yinliang Qi, Hong Zhou, Tingting Zhu, Li Liu, Yanan Gu, Kang Luan, Xin Luo, Sheng-quan Zhang*. Cholesterol partially rescues the inhibition effect of pravastatin on keratinocytes proliferation by regulating cell cycle relative proteins through AKT and ERK pathway. Dermatol Ther. 2020; 33(6): e14305. doi: 10.1111/dth.14305.
  4. Rui Jin#, Xin Luo, Kang Luan, Li Liu, Liang-Dan Sun, Sen Yang, Sheng- Quan Zhang*, Xue-Jun Zhang*. Disorder of the mevalonate pathway inhibits calcium-induced differentiation of keratinocytes. Mol. Med. Rep. 2017; 16 (4):4811-4816. doi: 10.3892/mmr.2017.7128.
  5. Xin Luo, Rui Jin#, Fang Wang, Bo Jia, Kang Luan, Feng-Wei Cheng, Lei Li, Liang-Dan Sun, Sen Yang, Sheng-Quan Zhang*, Xue-Jun Zhang*. Interleukin -15 inhibits the expression of differentiation markers induced by Ca(2+) in keratinocytes. Exp. Dermatol. 2016; 25(7):544-7. doi: 10.1111/exd.12992.
  6. Xuesai Zhang, Qingrou Li, Hui Zhao, Lanping Ma, Tao Meng, Jianchang Qian, Rui Jin, Jingkang Shen, Ker Yu*. Pathological expression of tissue factor confers promising antitumor response to a novel therapeutic antibody SC1 in triple negative breast cancer and pancreatic adenocarcinoma，Oncotarget 2017;10;8(35):59086-59102. doi: 10.18632/oncotarget.19175.

Patents

  1. “Targeting CD73 Antibody and Antibody-Drug Conjugates, Preparation Methods and Application Thereof”, Ker Yu, Rui Jin, Liang Liu. (2019) WO2019170131.
  2. “Targeting AXL Antibody and Antibody-Drug Conjugates, Preparation Methods and Application Thereof”, Ker Yu, Jingkang Shen, Tao Meng, Jinpeng Pei, Lanping Ma, Xin Wang, Rui Jin, Zhiyan Du, Lin Chen, Ting Yu, Yongliang Zhang.(2019) WO2019218944.